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  • Beta Arbutin Powder
    Beta arbutin
    Product name: beta arbutin Synonyms: β-arbutin INCI name: - CAS No.: 497-76-7 EINECS: 207-850-3 Quality: assay 99.5% by HPLC Molecular formula: C12H16O7 Molecular weight: 272.25   Description: β-Arbutin is used as a whitening ingredient for controlling the generation of melanin pigments, which are substances causing discoloration and freckles. It is known as a substance contained in ericaceous herbs called bearberry leaf. Discoloration and freckles occur due to reactive oxygen produced in skin by exposure to UV in sunlight, stress, atmospheric pollution, etc., which activates tyrosinase and the activated enzyme promotes the conversion of tyrosine in melanocytes (pigment cells) to melanin pigments. β-Arbutin is said to demonstrate whitening effects by reducing the production of melanin pigments by working directly on tyrosinase in melanocytes.   Specification (assay 99.5% by HPLC): Test Items Standard Appearance White crystalline powder Assay 99.5% min Melting point 198.5-201.5℃ Clarity of water solution Transparency, colorless, none suspended matters PH value of 1% aqueous solution 5-7 Specific optical rotation [α]D20=-66±2° Arsenic ≤2ppm Hydroquinone ≤10ppm Heavy metal ≤10ppm Loss on drying ≤0.5% Ignition residue ≤0.5% Pathogen Bacteria ≤300cfu/g Fungus ≤100cfu/g   Production capacity: 1000kg/month Storage condition: Stored in cool, dry place, room temperature. Package material: drum Package size:1kg/drum, 5kg/drum, 10kg/drum, 25kg/drum
  • snap 8 peptide
    snap 8
    Product name: SNAP-8 Synonyms:   INCI name:  CAS No.: 868844-74-0 Sequence: Ac-Glu--Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2  Quality: purity 98% up byHPLC Molecular formula:C41H70N16O16S Molecular weight:1075.2       Description: The anti wrinkle octapeptide SNAP-8 is an elongation of the famous hexapeptide ARGIRELINE. The study of the basic mechanism of anti-wrinkle activity led to the revolutionary hexapeptide which has taken the cosmetic world by storm. Those same studies have been applied to bring another addition to the Botulinum Toxin inspired family of peptides. It has been clearly established that these conformational changes and the disturbance of the perfect packing of the lipid matrix can be significantly avoided by modulating muscle contraction. SNAP-8 reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around eyes. SNAP-8 is a safer, cheaper, and milder alternative to Botulinum Toxin, topically targeting the same wrinkle formation mechanism in a very different way.   Specification (purity 98% up by HPLC): ITEMS SPECIFICATIONS Appearance White or off-white powder Identification  HPLC    Molecular Ion Mass     Retention time is same with the reference substance 1075.2   Purity (HPLC) : NLT 95.0% Related substances (HPLC) Total impurities: NMT 5.0% Any impurity: NMT 3.0%     Production capacity: 40kg/month Storage condition: with ice bag for transportation, 2-8℃ for long term storage Package material: vial, bottle Package size:1g/vial, 5/vial, 10g/vial, 50g/bottle, 500g/bottle
  • Pal-GHK -Bismancosmetic
    Pal-GHK
    Product name: Pal-GHK Synonyms:   INCI name:  CAS No.: Sequence: Pal-Gly-His-Lys-OH  Quality: purity 98% up byHPLC Molecular formula:C30H54N6O5 Molecular weight: 578.8   Description: PAL-GHK is also known as palmitoyl tripeptide-1 and is a small copper-binding peptide made up of three amino acids linked to a palmitate molecule. GHK was first discovered in human plasma and was found to be in significantly higher concentrations in plasma from young people when compared to the elderly; linking the peptide to aging. The peptide has a wide range of biological functions and has been found to regulate a huge number of proteins in the human body, with many being linked to health-promoting abilities. PAL-GHK stimulated genes essentially reset cells to a healthier, younger state. GHK was shown to stimulate many DNA repair genes and increase the expression of 14 genes linked to antioxidant production. These genetic modifications are proposed to reduce the signs of aging and remove free radicals and toxic agents that cause age-related diseases. These genetic changes also activate tissue healing and this has been demonstrated in rodents and pigs, where GHK was shown to stimulate whole-body healing. When GHK was injected into rat muscle it caused rapid wound healing and this was also demonstrated in mice. In pigs, the peptide was able to heal surgical defects, even when injected at a location that was distant from the wound. The peptide can also heal bone fractures and this has been confirmed in rats. The PAL-GHK peptide also plays a major role in skin regeneration and can be used for cosmetic purposes, where it is marketed as copper-tripeptide 1. GHK can stimulate a number of structural molecules found in the skin, including collagen, dermatan sulphate, chondroitin sulphate, and decorin. In cosmetics, the peptide tightens skin and improves elasticity, skin density, and firmness, leading to a reduction in fine lines and wrinkles. A number of studies have shown that creams containing GHK can significantly increase collagen production and that they improve skin clarity and appearance and increase skin density and thickness.   Specification (purity 98% up by HPLC): Items Standards Appearance White or off white powder Identity Monoisotopic mass:578.8±1.0 Peptide purity(HPLC) ≥95.0% by area integration Water content ≤5.0% HAC content(by HPLC) ≤15.0%       Production capacity: 40kg/month Storage condition: with ice bag for transportation, 2-8℃ for long term storage Package material: vial, bottle Package size:1g/vial, 5/vial, 10g/vial, 50g/bottle, 500g/bottle
    Tags : Pal-GHK
  • Pal-AHK -Bismancosmetic
    Pal-AHK
    Product name: Pal-AHK Synonyms:   INCI name:  CAS No.: 147732-56-7 Sequence: Pal-Ala-His-Lys-OH  Quality: purity 98% up byHPLC Molecular formula:C31H56N6O5 Molecular weight:592.81   Description: Palmitoyl Tripeptide (Pal AHK) effectively increase collagen and elastin production. It prevent hair loss, promote wound healing improve hair growth and supply nutrients for hair growth. Pal-AHK is a synthetic peptide in which AHK has been linked to a palmitoyl fatty acid molecule. The fatty acid makes AHK more fat suluble, which not only increases its skin penetration, but actually increases the absorption of the molecule by cells. Once in the cell, Pal-GHK is thought to activate fibroblasts by stimulating TGF-1.   Pal-AHK can activate fibroblasts and thus increase the rate of extracellular matrix (ECM) production in the skin. The ECM is composed of a number of molecules, with collagen and elastin being the most abundant in many cases. By boosting ECM production, Pal-AHK increases collagen and elastin levels within the skin. This, in turn, improves skin appearance and strength. There is also some evidence, from benchtop experiments, that pal-AHK can influence the production of vascular endothelial growth factor (VEGF). VEGF is a important signaling molecule in the production of new blood vessels. By encouraging blood vessel growth in the skin, Pal-AHK has demonstrated increased skin rejuvenation and hair growth in animal models.       Specification (purity 98% up by HPLC):   Items Standards Appearance White to yellowish powder Purity (HPLC) ≥95% Identification (MS) 592.43±1 Impurity (HPLC) ≤5.0% Water (KF) NMT5.0%       Production capacity: 40kg/month Storage condition: with ice bag for transportation, 2-8℃ for long term storage Package material: vial, bottle Package size:1g/vial, 5/vial, 10g/vial, 50g/bottle, 500g/bottle
    Tags : Pal-AHK
  • Matrixyl powder
    Matrixyl
    Product name: Matrixyl Synonyms:   INCI name:  CAS No.: 214047-00-4 Sequence: Pal-Lys-Thr-Thr-Lys-Ser-OH  Quality: purity 98% up byHPLC Molecular formula:C39H75N7O10 Molecular weight:802.05   Description: Matrixyl is powerful peptide with strong anti-ageing benefits.   It helps to even out skin tone and smoothes wrinkles from the inside by rebuilding the skin. It supports facial structures and regulates cell activity while protecting, repairing and strengthening damaged skin. It stimulates the production of collagen and hyaluronic acid which improves skin moisture and elasticity levels and aids in refilling wrinkles making the skin look plump and youthful.   Matrixyl targets problems areas such as sagging skin and worry lines, forehead wrinkles and crow's feet, smoothing their appearance so they look visibly diminished.       Specification (purity 98% up by HPLC): TEST ITEMS SPECIFICATION Appearance White to off-white powder Molecular Ion Mass 802.05±1 Purity (HPLC) NLT 95%   Related substances (HPLC) Total impurities: NMT 5.0% Any impurity: NMT 2.0% Acetic acid (HPLC) NMT 15% Water (Karl Fischer) NMT 8.0%     Production capacity: 40kg/month Storage condition: with ice bag for transportation, 2-8℃ for long term storage Package material: vial, bottle Package size:1g/vial, 5/vial, 10g/vial, 50g/bottle, 500g/bottle
  • Lipopeptide -Bismancosmetic
    Lipopeptide
    Product name: Lipopeptide Synonyms: Lipopeptide acetate  INCI name:  CAS No.: 171263-26-6 Sequence: Pal-Val-Gly-Val-Ala-Pro-Gly-OH  Quality: purity 98% up byHPLC Molecular formula:C38H68N6O8 Molecular weight:736.98   Description: Lipopeptides (LPs) are a class of microbial secondary metabolites constituting diverse biological functions for example working as a surface active agent (surfactant) featuring antimicrobial or cytotoxic activities. Lipopeptides constitute a structurally diverse group of metabolites produced by various bacterial and fungal genera. In the past decades, research on lipopeptides has been fueled by their antimicrobial, antitumour, immunosuppressant and surfactant activities. However, the natural functions of lipopeptides in the lifestyles of the producing microorganisms have received considerably less attention. The substantial structural diversity of lipopeptides suggests that these metabolites have different natural roles, some of which may be unique to the biology of the producing organism.       Specification (purity 98% up by HPLC): TEST ITEMS SPECIFICATION Appearance White or almost white powder Molecular Ion mass 736.98±1 Purity (HPLC) NLT 95% Related substances (HPLC) Total impurities: NMT 5.0% Any impurity: NMT 1.5% Water (Karl fishcer) NMT 8.0% Acetic acid (HPLC) NMT 15.0% Production capacity: 40kg/month Storage condition: with ice bag for transportation, 2-8℃ for long term storage Package material: vial, bottle Package size:1g/vial, 5/vial, 10g/vial, 50g/bottle, 500g/bottle
  • Leuphasyl -Bismancosmetic
    Leuphasyl
    Product name: Leuphasyl Synonyms: D-ALA2 INCI name: - CAS No.: 64963-01-5 Sequence: L-Tyr-D-Ala-Gly-L-Phe-L-Leu-OH  Quality: purity 98% up by HPLC Molecular formula:C29H39N5O7 Molecular weight:569.65   Description: Leuphasyl is a peptide to reduce expression wrinkles. Leuphasyl offers several advantages: A new and alternative in vitro mechanism to fight expression wrinkles An additive / synergistic effect to complement the action of Argireline and other peptides Reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes. Targets in vitro the wrinkle-formation mechanism of expression wrinkles in a new way, offering an alternative to peptides like Argireline®. Can be incorporated in cosmetic formulations such as emulsions, gels, serums, etc., where removal of the deep lines or wrinkles in the forehead or around the eye area is desired.       Specification (purity 98% up by HPLC): TEST SPECIFICATION Appearance White or pale yellow powder MS 568.66±1 Purity (by HPLC) ≥90.0% Production capacity: 40kg/month Storage condition: with ice bag for transportation, 2-8℃ for long term storage Package material: vial, bottle Package size:1g/vial, 5/vial, 10g/vial, 50g/bottle, 500g/bottle
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