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  • Minoxidil Powder
    Minoxidil
    Product name: Minoxidil Synonyms:  INCI name: Minoxidil CAS No.: 38304-91-5 EINECS: 253-874-2 Quality: USP43 Molecular formula:C9H15N5O Molecular weight: 209.25   Description: Minoxidil was first introduced as an antihypertensive medication and the discovery of its common adverse event, hypertrichosis, led to the development of a topical formulation for promoting hair growth. To date, topical minoxidil is the mainstay treatment for androgenetic alopecia and is used as an off-label treatment for other hair loss conditions. Despite its widespread application, the exact mechanism of action of minoxidil is still not fully understood. In this article, we aim to review and update current information on the pharmacology, mechanism of action, clinical efficacy, and adverse events of topical minoxidil.   Minoxidil also works by increasing the supply of blood and nutrients to your hair follicles helping to strengthen the existing hairs and encouraging them to grow   Minoxidil is the only over- the-counter active ingredient clinically proven to help stop and even reverse hereditary hair loss, by reactivating your inactive hair follicles.   The mechanism by which minoxidil stimulates hair growth is not fully understood, but minoxidil can help reverse the hair loss process of androgenetic alopecia by the following means:   Reverses the miniaturisation of follicles Increases blood flow around follicles Stimulates follicle movement to growth phase Extends each follicle growth phase     Specification (USP43):   Items Specifications Appearance White to off-white crystal powder Identification IR: similar to the reference standard Melting point 248-268℃ Solubility Soluble in propylene glycol, sparingly soluble in methanol. Slightly soluble in water. Practically insoluble in chloroform, in acetone, in ethyl acetate and in hexane. Residue on ignition ≤0.5% Elemental impurities ≤20ppm Loss on drying ≤0.5% Organic volatile impurities Meet the requirements Residual solvents Methanol≤3000ppm Ethanol≤5000ppm Ethyl acetate≤5000ppm Total impurities ≤1.5% Assay(HPLC) 97~103%       Production capacity: 1000kg/month Storage condition: Stored in cool, dry place, room temperature. Package material: drum Package size:1kg/drum, 5kg/drum, 10kg/drum, 25kg/drum
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